After steady state is achieved, the rate of insulin absorption and insulin elimination is equal.2
Here’s why once-daily Tresiba® may be appropriate for your pediatric patients
Engineered to provide a long duration of action that won’t taper off at the end of the day.1,2,a
Tresiba® FlexTouch® is a prefilled insulin pen with no push-button extension.
Adult patients who miss a dose of Tresiba® should inject their daily dose during waking hours upon discovering the missed dose, then continue with their regular dosing schedule. Ensure that at least 8 hours have elapsed between Tresiba® injections.1 If a pediatric patient misses a dose, they should contact their health care provider for guidance and monitor blood glucose levels more frequently until the next scheduled dose.
Population pharmacokinetic analysis was conducted for Tresiba® using data from 199 pediatric subjects (1 to <18 years of age) with type 1 diabetes. Body weight was a significant covariate affecting the clearance of Tresiba®. After adjusting for body weight, the total exposure of Tresiba® at steady state was independent of age.
The safety and effectiveness of Tresiba® to improve glycemic control in type 1 and type 2 diabetes have been established in pediatric patients 1 year of age and older. The safety and effectiveness of Tresiba® have not been established in pediatric patients less than 1 year old. The use of Tresiba® in pediatric patients 1 year of age and older with type 1 and type 2 diabetes is supported by evidence from an adequate and well-controlled study and a pharmacokinetic study (studies included pediatric patients 1 year of age and older with type 1 diabetes mellitus). The use of Tresiba® in pediatric patients 1 year of age and older with type 2 diabetes is also supported by evidence from adequate and well-controlled studies in adults with type 2 diabetes.
Pediatric patient resource center
The amount of information families have to take in when starting a child on a diabetes care plan may be daunting. The Tresiba® pediatric resource center provides downloads about basal insulin therapy and managing blood glucose in children with diabetes as well as guidance for helping children and their families navigate a diagnosis.
Dive deeper into Tresiba®
aAfter the last of 8 once-daily injections (0.4 units/kg).
bFor up to 24 months. Maximum savings $500 per prescription. Eligibility and other restrictions apply.
cYou must be a licensed practitioner who can legally prescribe medication in your state. (Request for product samples is limited to 1 request per health care professional.)