same unit dose as total daily long- or intermediate-acting insulin dose
How to start your adult patients on Tresiba®
Step 1: Initiate1
Type 1 diabetes
Insulin naïve
1/3 to 1/2
of total daily insulin dosea
Type 2 diabetes
Insulin naïve
10 units
once daily
1:1 CONVERSION
aThe remainder of the total daily insulin dose should be administered as a short-acting insulin and divided between each daily meal. As a general rule, 0.2 to 0.4 units of insulin per kilogram of body weight can be used to calculate the initial total daily insulin dose in insulin-naïve patients with type 1 diabetes.
Step 2: Titrate2-4
Based on ADA and AACE Guidelines2,3


The recommended time between dose increases is 3 to 4 days1
- Tresiba® was not studied in clinical trials using this algorithm
- Individualize and titrate the dose of Tresiba® based on the patient’s metabolic needs, blood glucose monitoring results, and glycemic control goal. Dose adjustments may be needed with changes in physical activity, changes in meal patterns, changes in renal or hepatic function, or during acute illness to minimize the risk of hypoglycemia or hyperglycemia1

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Tresiba® patient support brochure
Give your patients information on how to use Tresiba® FlexTouch® and how to get savings and support.
Find out how to prescribe Tresiba® for your pediatric patients
Add Tresiba® to your ePrescribing system
Tresiba® FlexTouch® U-100

Form/Strength:
100 units/mL
Quantity per box:
15 mL (5 x 3 mL)
1500 units total
NDC:
0169-2660-15
Tresiba® FlexTouch® U-200

Form/Strength:
200 units/mL
Quantity per box:
9 mL (3 x 3 mL)
1800 units total
NDC:
0169-2550-13
Tresiba® U-100,
10-mL vial

Form/Strength:
100 units/mL
Quantity per box:
1 vial (10 mL)
1000 units total
NDC:
0169-2662-11
Prescribing Tresiba®
When sending prescribing information, be sure to specify the right formulation of Tresiba® for your patients:
- The U-100 pen has a maximum dose of 80 units per injection and is dosed in 1-unit increments
- The U-200 pen has a maximum dose of 160 units per injection and is dosed in 2-unit increments
- The U-100 vial holds a volume of 10 mL
Also be sure to include:

Starting dose (units per day)

Titration information

Separate prescription for pen needles (if necessary)
