A smooth and steady release provides continuous coverage for longer than 24 hours
Here’s why once-daily Tresiba® may be appropriate for your pediatric patients
aAfter the last of 8 once-daily injections (0.4 units/kg).
If a pediatric patient misses a dose, they should contact their health care provider for guidance and monitor blood glucose levels more frequently until the next scheduled dose. Adult patients who miss a dose of Tresiba® should inject their daily dose during waking hours upon discovering the missed dose, then continue with their regular dosing schedule. Ensure that at least 8 hours have elapsed between Tresiba® injections.1
Population pharmacokinetic analysis was conducted for Tresiba® using data from 199 pediatric subjects (1 to <18 years of age) with type 1 diabetes. Body weight was a significant covariate affecting the clearance of Tresiba®. After adjusting for body weight, the total exposure of Tresiba® at steady state was independent of age.
The safety and effectiveness of Tresiba® to improve glycemic control in type 1 and type 2 diabetes have been established in pediatric patients 1 year of age and older. The safety and effectiveness of Tresiba® have not been established in pediatric patients less than 1 year old. The use of Tresiba® in pediatric patients 1 year of age and older with type 1 and type 2 diabetes is supported by evidence from an adequate and well-controlled study and a pharmacokinetic study (studies included pediatric patients 1 year of age and older with type 1 diabetes mellitus). The use of Tresiba® in pediatric patients 1 year of age and older with type 2 diabetes is also supported by evidence from adequate and well-controlled studies in adults with type 2 diabetes.
Tresiba® pediatric patient resource center
The amount of information families have to take in when starting a child on a diabetes care plan may be daunting. The Tresiba® pediatric resource center provides downloads about basal insulin therapy and managing blood glucose in children with diabetes as well as guidance for helping children and their families navigate a diagnosis.